I had always had the mistaken understanding that the acronym TWAIN (a standard for imaging peripherals) was a facetious title meaning "Technology Without an Interesting Name." In the past, I've even been duped into spreading this fallacy to friends and family. Well, I'm ignorant no longer. While searching for something today, I discovered that according to The Free On-line Dictionary of Computing and substantiated by the TWAIN Working Group's official website, it's not an acronym at all:

The word TWAIN is from Kipling's "The Ballad of East and West" - "...and never the twain shall meet...", reflecting the difficulty, at the time, of connecting scanners and personal computers. It was up-cased to TWAIN to make it more distinctive. This led people to believe it was an acronym, and then to a contest to come up with an expansion. None were selected, but the entry "Technology Without An Interesting Name" continues to haunt the standard.

The Free On-line Dictionary of Computing, Editor Denis Howe